Arizona Cardinals vs. San Francisco 49ers 10-01-23 NFL Week 4 Analysis, Best Picks, and Odds

Arizona Cardinals vs. San Francisco 49ers 10/01/23 – In what promises to be a captivating Week 4 clash, the Arizona Cardinals will look to even their season record as they face the undefeated San Francisco 49ers. With contrasting early-season trajectories, both teams are set to bring their A-game to Levi’s Stadium. Football enthusiasts and punters searching for daily football picks are undoubtedly keeping a keen eye on this matchup.

Arizona Cardinals vs. San Francisco 49ers

Date & Time: Sunday, October 1, 2023, at 4:25 PM ET

Location: Levi’s Stadium


Arizona Cardinals vs. San Francisco 49ers 10/01/23 Betting Odds

Arizona Cardinals+625+14.5 (-112)41 over (-111)
San Francisco 49ers-950-14.5 (-110)41 under (-111)

Arizona Cardinals Analysis

The Cardinals, with a 1-2 start, still show signs of being a competitive force this season. Offensively, QB Joshua Dobbs has demonstrated proficiency, showcasing a commendable 68.9% completion rate in his first two games. However, his 3 interceptions and only 3 touchdowns indicate some decision-making issues under pressure. James Conner, while having a lackluster average with 1.6 yards per attempt, will need to step up against the 49ers’ dominant defense. On the receiving end, Marquise Brown has emerged as a reliable target, averaging a respectable 9.1 yards per reception.

Defensively, the Cardinals have a challenge on their hands. Given the 49ers’ formidable offense, Arizona needs to focus on strengthening their defensive line and ensuring their secondary can handle the 49ers’ aerial assault. The team will lean on their past experience, as they have a decent track record against the 49ers, to boost their confidence.

San Francisco 49ers Analysis

Undefeated San Francisco comes into this game with an air of dominance. Quarterback Brock Purdy has impressed in his first three outings, boasting a completion percentage of 67 and an impressive passer rating of 106.3. Christian McCaffrey, the powerhouse running back, averages a tremendous 5.9 yards per attempt and has already found the end zone thrice this season. Wide receiver Deebo Samuel, with an average of 14.5 yards per reception, is proving to be a key asset for Purdy.

On the defensive side, the 49ers will want to capitalize on Dobbs’ early-season interceptions, aiming to pressure him into making mistakes. They’ll also look to contain Brown and restrict his yards after catch. With their current form and home advantage, they are poised to give the Cardinals a challenging afternoon.

Arizona Cardinals vs. San Francisco 49ers Against the Spread

Arizona, despite their shaky start to the season, has shown resilience against the spread, going 5-1 ATS in their last 6 games. Their historic 11-5 SU record against San Francisco showcases that they often rise to the occasion against their NFC West rivals. However, their 1-6 SU in recent road games paints a grim picture for the upcoming game at Levi’s Stadium.

The 49ers, on the other hand, have been stellar, both on the field and for the bettors. An 11-3 ATS in their last 14 games is testament to their consistent performances. Notably, when playing at home against the Cardinals, totals often lean towards the “over,” suggesting we might be in for an offensive showcase from both teams.

Arizona Cardinals vs. San Francisco 49ers Free Pick

Based on odds, trends, team stats, and key players, here are the picks:

Moneyline: 49ers -950

While the Cardinals have historically played the 49ers tough, San Francisco’s current form suggests they will maintain their unbeaten run. 

Spread: Cardinals +14.5 (-112)

Given the Cardinals’ record against the spread and their ability to challenge the 49ers historically, the +14.5 spread for Arizona seems too generous. 

Total: 41 over (-111)

Based on the recent trends, especially with the games played at Levi’s Stadium between these teams, the over looks promising. 

Predicted Score: San Francisco 49ers 27, Arizona Cardinals 17

In conclusion, while the San Francisco 49ers have had a blistering start to the season, the Arizona Cardinals are no pushovers, especially considering their recent history against the 49ers. Both teams possess the offensive firepower to light up the scoreboard, making this one of the must-watch games of the week. For those interested in Canadian sports betting, this matchup offers some intriguing opportunities.