New York Giants vs. San Francisco 49ers 09-21-23 NFL Week 3 Analysis, Best Picks, and Odds

New York Giants vs. San Francisco 49ers 09/21/23 – As NFL season 3 rolls forward, fans and bettors alike will witness an intriguing matchup between the New York Giants and San Francisco 49ers on September 21, 2023 at 8:15 PM ET at Levi’s Stadium – promising an exhilarating contest that could significantly change both teams’ prospects in 2023. Many will look forward to making winning NFL picks in this contest; thus making this matchup essential viewing!

New York Giants vs. San Francisco 49ers

Date & Time: Wednesday, September 21 at 8:15 PM ET

Location: Levi’s Stadium


New York Giants vs. San Francisco 49ers 09/21/23 Betting Odds


New York Giants Analysis

New York Giants offense faces an uphill climb. Quarterback Daniel Jones has struggled, posting only 53.6 completion rate and 32.4 passer rating. Additionally, he threw just 104 yards per game without touchdown passes. With no air efficiency available to them, more pressure falls onto their running game, especially key running back Saquon Barkley who averages an impressive average 4.3 yards per rush on 12 attempts; an encouraging sign but far from enough to secure victory on its own.

Defensively, the Giants find themselves vulnerable. They have shown weaknesses against teams with powerful offenses in previous matches; these weaknesses were especially evident against San Francisco 49ers team which has shown proficiency with aerial attacks. An absence of data regarding sack numbers and turnovers suggests playmaking issues may arise with regard to Giants defense that must step up their game against San Francisco’s explosive offense to remain competitive.

San Francisco 49ers Analysis

San Francisco 49ers quarterback Brock Purdy has made an immediate impactful statement this season with his incredible 65.5% completion rate and 111.3 passer rating, averaging 220 passing yards per game while throwing two touchdown passes without an interceptions – stats which show how efficient yet careful with his ball handling he can be; any defense must work to contain him effectively! Running back Christian McCaffrey has also been amazing, amassing 152 rushing yards in one game alone while averaging 6.9 yards per rush!

On defense, the 49ers appear strong and have shown few vulnerabilities compared to their Giants opponents. Their win streak indicates a resilient defense capable of holding its own against high-scoring teams; while specific stats are unavailable they have excelled in important aspects like pass rush and secondary play in previous performances. Though strong defensively overall, Saquon Barkley could pose a threat on the ground which makes their rush defense all the more important for success against him and will need to be managed accordingly by San Francisco.

New York Giants vs. San Francisco 49ers Against the Spread

The Giants have posted an overall record of 12-6 against the spread (ATS) over their last 18 games, but have struggled against San Francisco 49ers recently, going 1-4 against them in their five matchups (1-4 in terms of total points scored versus 8-3 for total losses on the road). Nonetheless, their road record stands out: 8-3 overall during those 11 contests!

On the contrary, the 49ers have posted an impressive 10-3 ATS record over their last 13 games and 14-1 SU record over 15 contests. At home they have been near flawless, going 7-0 against the spread in their last 7 home contests; however, against Giants they have struggled more at two out of seven attempts with an ATS record of 2-5 against them at home.

New York Giants vs. San Francisco 49ers Free Pick

Based on odds, trends, team stats, and key players, here are the picks:

Moneyline: My moneyline pick is for the San Francisco 49ers. The team’s recent performance and key player stats make them a favorable choice.

Spread: I’d go with the Giants to cover the spread of +10.5. Given their recent success on the road, they might keep the game closer than expected.

Total: Considering both team’s offensive capabilities, I would pick the over on the total of 45.5.

Predicted Score: San Francisco 49ers 28, New York Giants 20

Overall, Week 3 promises to be an intriguing contest that holds major ramifications for both teams involved. Live betting in Canada or elsewhere offers numerous lucrative opportunities that should provide exciting action on game day.